This project aims at elucidating the role of chemical cross-talk in triggering metabolite production and in mediating the interaction between two fungi, the mycoparasite Trichoderma atroviride and the plant pathogen Botrytis cinerea (grey mold).
Das CD-Labor für invasive Pilzinfektionen unter der Leitung von Univ.-Prof.in Cornelia Lass-Flörl, Direktorin der Sektion für Hygiene und Medizinische Mikrobiologie, forscht an der Entwicklung innovativer Strategien für die Diagnose und Therapie von Infektionen (Pilze und nosokomiale Infektionen).
CURCUCONT - (acronym for Curculionidae Control) is a joint project of University Innsbruck and AGRANA Research & Innovation Center GmbH. to characterise the natural entomopathogenic antagonist M. brunneum BIPESCO 5 in Bothynoderes punctiventris infested areas in Lower Austria.
DIACONT - (Diabrotica control, 2015-2018) Alternative methods of protection of maize from Western Corn Rootworm (Diabrotica v. virgifera).
This project investigates chitin synthases and chitin deacetylases and their role in mycoparasitism as well as vegetative growth.
Recently we have shown that chitin and chitosan act as key elements in the remodeling of cell walls during mycoparasitism. We believe that converting chitin to chitosan could serve as a disguise strategy and as a scavenger for oxidative stress from phytopathogens. With our approach, we will be able to draw the first, holistic picture of the spatial and interdependent processes of cell wall remodeling in T. atroviride as model organism for mycoparasitism.
In collaboration with Prof. Gerhard Schütz Biophysics group (Vienna University of Technology) we are analysing single molecule dynamics during mycoparasitic attack.
RpdA is an essential HDAC of pathogenic species such as Aspergillus fumigatus and Aspergillus terreus. We are analyzing (novel) RpdA-inhibitors with regard to their antifungal activity.
Aim of the project is to get intsights into shared and monopolised processes in phytomyxid parasites of plants and brown algae.
(Infection & Immunity: Innate Immunity – Host & Pathogen, Antifungal Host Response) - Scientists and physicians of the Innsbruck campus, working in the related fields of Infection, Immunity, Transplantation and/or Biogerontology decided to join forces and created a structured and multidisciplinary research and training programme of excellence.
Hundreds of alpine fungal taxa have been newly described from alpine habitats such as Salix herbacea, Dryas octopetala or Kobresia myosuroides habitats since the pioneering work of Jules Favre in the 1950ties. The main question is, whether these are good species or adaptations to an extreme habitat.
SM are small bioactive molecules that are critical for fungal species during their development and interaction with other organisms. We are analyzing the impact of specific HDACs on the regulation of important SMs such as toxins and antibiotics.
MELBEAUPOP - (acronym for Melolontha Beauveria Population structure) is a joint project of the Agroscope Reckenholz, Swiss Federal Institute for Forest, Snow and Landscape Research WSL and University Innsbruck to monitor and characterise the natural entomopathogenic antagonist B. brongniartii in cockchafer infested areas in East-, North- and South Tyrol and Switzerland.
MELOBEAUMON - Melolontha spp. and Beauveria brongniartii monitoring in cockchafer infested areas in North and East Tyrol.
MELOPHYL - (acronym for Melolontha and Phyllopertha Control) is a joint project of Bezirkslandwirtschaftskammer Landeck, Amt der Tiroler Landesregierung – Gruppe Agrar and University Innsbruck, to characterise the persistence of two entomopathogenic fungal antagonists – Beauveria brongniartii BIPESCO 2 and Metarhizium brunneum BIPESCO 5 - in Scarabaeidae infested areas in North Tyrol (Austria).
The project is funded by Amt der Tiroler Landesregierung (Vertragsnummer: 016135).
Snow-covered landscapes suggest an image of dormancy and hibernation. However, underneath the snow cover soil is teeming with microbial activity. The project “MICINSNOW - Microbial Interactions in Snow Covered Habitats” investigates winter-active soil microbial communities (MCs) and their interactions.
OPATHY (from Omics of PATHogenics Yeasts) is an innovative translational research training network that will explore the potential of next-generation high-throughput technologies, including genomics, transcriptomics and proteomics, to study the interactions of yeasts that cause disease to humans (e.g. Candida and Cryptococcus sp.) with their host, and to develop new diagnostic tools to monitor yeast infections in the clinic.
Proteomic and transcriptomic analyses to (i) characterize novel substrates and (ii) to investigate the contribution of HDACs and PRMTs to the regulation of secondary metabolism as well as of stress response genes.
Antifungal proteins from Ascomycetes contain a structurally conserved motif that resembles the Greek letter “gamma”: the gamma-core.
Secondary Metabolism in the Mycoparasite Trichoderma atroviride: Genes, Pathways and Regulation